Chemical Profiles, In Vitro Antioxidant and Antifungal Activity of Four Different Lavandula angustifolia L. EOs

Abstract

Lavandula angustifolia L., known as lavender, is an economically important Lamiaceae due to the production of essential oils (EOs) for the food, cosmetic, pharmaceutical and medical industries. The purpose of this study was to determine the chemical composition of EOs isolated from four inflorescences of L. angustifolia L. collected in different geographical areas: central-southern Italy (LaCC, LaPE, LaPS) and southern France (LaPRV). The essential oils, obtained by steam distillation from plants at the full flowering stage, were analyzed using gas chromatography coupled with mass spectrometry (GC-MS). More than 70 components identified in each sample showed significant variability among the main constituents. The four EOs analyzed contained the following as main component: linalool (from 30.02% to 39.73%), borneol (13.65% in LaPE and 16.83% in La PS), linalyl acetate (24.34% in LaCC and 31.07% in LaPRV). The EOs were also evaluated for their in vitro antifungal activity against two white rot fungi (Phanerochaete chrysosporium and Trametes cingulata) as potential natural biodeteriogens in the artworks field, and against Sclerotium rolfsii, Botrytis cinerea and Fusarium verticilloides responsible for significant crop yield losses in tropical and subtropical areas. The results confirm a concentration-dependent toxicity pattern, where the fungal species show different sensitivity to the four EOs. The in vitro antioxidant activity by DPPH assay showed better scavenging activity on LaCC (IC50 26.26 mg/mL) and LaPRV (IC50 33.53 mg/mL), followed by LaPE (IC50 48.00 mg/mL) and LaPS (IC50 49.63 mg/mL). The potential application of EOs as a green method to control biodeterioration phenomena on a work of art on wood timber dated 1876 was evaluated.

Recent Advances in Chemistry and Antioxidant/Anticancer Biology of Monoterpene and Meroterpenoid Natural Product

“…Linalyl acetate ( 3b , Figure 3 ) has been well documented to have favorable bioactivities. Anticancer properties have been associated with essential oils from Lavandula angustifolia, Lavandula officinalis, Lavandula latifolia , and bergamot [ 40 , 41 , 42 , 43 , 44 ], all of which contain linalyl acetate in concentrations as high as 44%. A study conducted on the lavender essential oils from Lavandula angustifolia demonstrated an IC 50 values of 0.36% ( v / v ) against HaCaT cell line in an MTT assay [ 43 ].…”

“…Anticancer properties have been associated with essential oils from Lavandula angustifolia, Lavandula officinalis, Lavandula latifolia , and bergamot [ 40 , 41 , 42 , 43 , 44 ], all of which contain linalyl acetate in concentrations as high as 44%. A study conducted on the lavender essential oils from Lavandula angustifolia demonstrated an IC 50 values of 0.36% ( v / v ) against HaCaT cell line in an MTT assay [ 43 ]. Additionally, there have been reports of linalyl acetate associated antioxidant activity in essential oils of Salvia sclarea , and Myrtus nivellei , across different regions [ 45 , 46 ].…”

Lavender essential oil - properties and uses

“…angustifolia L., събрани oт централна и южна Италия и Южна Франция, като са изследвани тяхната in vitro противогъбична активност срещу две гъбички, причиняващи бяло гниене (Phanerochaete chrysosporium и Trametes cingulata), както и спрямо Sclerotium rolfsii, Botrytis cinerea и Fusarium verticilloides, които били причина за значителни загуби на реколта в тропическите и субтропичните райони. Резултатите потвърждават чувствителността им към четирите лавандулови масла (Caprari et al, 2023).…”

Phytochemical Composition and Antimicrobial Properties of New Lavandula angustifolia Ecotypes

“…The composition and proportions of bioactive ingredients in extracts obtained from lavender raw materials determine its biological functions and potential applications. Due to its proven antibacterial [19], antifungal [20], antioxidant [21], and anti-inflammatory [22] properties, this plant is very popular among both breeders and potential recipients of the raw material. Numerous scientific publications devoted to the chemical analysis of the raw material also demonstrate great interest [23,24].…”