“…6,12 Our group also has access to data from the Brazilian Federal Police chemical profiling program based on the quantification of coca alkaloids and pharmaceuticals used as adulterants such as caffeine, lidocaine, levamisole and phenacetin, in seized cocaine samples. 13,14 Due to the near real-time characteristics of the WBDE approach, consumption estimates can be assessed in order to identify drug use variations according to different seasons, [15][16][17] days of a week, 16 and even recreational events. 18 Gerrity et al 19 investigated temporal variability associated with the 2009 National Football League's Super Bowl, a significant weekend for tourism in the event area, given the potential for unusual flow patterns and mass loadings of pharmaceuticals, personal care products and illicit drugs.…”