1993
DOI: 10.1021/cr00021a001
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Chemical studies of marine bacteria: developing a new resource

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Cited by 410 publications
(253 citation statements)
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References 30 publications
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“…Comparison of the 13 C-NMR data of essramycin with values of related synthetic compounds of type 1 delivered, however, a much better agreement with the experimental values than with compounds of type 2, confirming the skeleton of 1 [15,16]: A C-2 substituent affects the ipso C atom of 1,2,4-triazolo[1,5-a]pyrimidines, however, the influence on the 13 C shifts of the other ring atoms is negligible (Table 4). [1,2,4]Triazolo[1,5-a]pyrimidines have found a broad interest as fungicides [17], herbicide safener [18,19], kinase inhibitors [20,21], antiparasitic [22] and plant protecting agents [23]. Thousands of compounds of this type have been described, however, to the best of our knowledge, not a single natural product is amongst them [6,24,25].…”
Section: Resultsmentioning
confidence: 99%
“…Comparison of the 13 C-NMR data of essramycin with values of related synthetic compounds of type 1 delivered, however, a much better agreement with the experimental values than with compounds of type 2, confirming the skeleton of 1 [15,16]: A C-2 substituent affects the ipso C atom of 1,2,4-triazolo[1,5-a]pyrimidines, however, the influence on the 13 C shifts of the other ring atoms is negligible (Table 4). [1,2,4]Triazolo[1,5-a]pyrimidines have found a broad interest as fungicides [17], herbicide safener [18,19], kinase inhibitors [20,21], antiparasitic [22] and plant protecting agents [23]. Thousands of compounds of this type have been described, however, to the best of our knowledge, not a single natural product is amongst them [6,24,25].…”
Section: Resultsmentioning
confidence: 99%
“…Lately marine bacteria have roused interest due to their unique secondary metabolites which differ significantly from the ones produced by terrestrial counterparts [1,2]. During our screening for metabolites with antimicrobial activities, Salegentibacter sp.…”
Section: Introductionmentioning
confidence: 99%
“…As part of our ongoing studies to develop the biomedical potential of marine microorganisms (e.g. Fenical, 1993;Liu et al, 2003;Oh et al, 2005), we examined marine fungi isolated from ocean muds collected at various depths. Here, we report the structures of two new metabolites, spiromassaritone (1) and massariphenone (2), and two known fungal metabolites, 6-epi-5′-hydroxy-mycosporulone (3) and enalin A (4), from cultures of a sterile fungal strain isolated from a mud sample collected at 5 meter depth adjacent to the Palau Islands in the Pacific Ocean.…”
Section: Introductionmentioning
confidence: 99%