Chemical synthesis of the organoarsenical antibiotic arsinothricin

Howlader, A. Hasan; Suzol, Sazzad H.; Nadar, Venkadesh Sarkarai; Galván, Adriana E; Nedovic, Aleksandra; Čudić, Predrag; Rosen, Barry P.; Yoshinaga, Masafumi; Wnuk, Stanislaw F.

doi:10.1039/d1ra06770b

RSC Adv.

2021

DOI: 10.1039/d1ra06770b

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Chemical synthesis of the organoarsenical antibiotic arsinothricin

A. Hasan Howlader

Sazzad H. Suzol

Venkadesh Sarkarai Nadar

et al.

Abstract: Arsinothricin is prepared from 2-chloroethyl(methyl)arsinic acid or by reduction of N-acetyl protected derivative of hydroxyarsinothricin and methylation with methyl iodide.

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One-Pot Chemoenzymatic Synthesis of Arsinothricin and the Mechanistic Insights into the Noncanonical Radical SAM Enzyme ArsL

Li,

Chen,

Ding

et al. 2024

ACS Catal.

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One-Pot Chemoenzymatic Synthesis of Arsinothricin and the Mechanistic Insights into the Noncanonical Radical SAM Enzyme ArsL

Li,

Chen,

Ding

et al. 2024

ACS Catal.

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Chemical synthesis of the organoarsenical antibiotic arsinothricin

Abstract: Arsinothricin is prepared from 2-chloroethyl(methyl)arsinic acid or by reduction of N-acetyl protected derivative of hydroxyarsinothricin and methylation with methyl iodide.

Cited by 1 publication

References 15 publications

One-Pot Chemoenzymatic Synthesis of Arsinothricin and the Mechanistic Insights into the Noncanonical Radical SAM Enzyme ArsL

One-Pot Chemoenzymatic Synthesis of Arsinothricin and the Mechanistic Insights into the Noncanonical Radical SAM Enzyme ArsL

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