Chemical toxicity screening of tire particle leachates from vehicles and their effects on organisms across three trophic levels

Kim, Lia; Kim, Haemi; Lee, Tae-Yang; An, Youn‐Joo

doi:10.1016/j.marpolbul.2023.114999

Cited by 13 publications

(3 citation statements)

References 42 publications

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“…There is still a high level of uncertainty concerning the impact of TWPs on marine ecosystems. This is complicated by the fact that chemical composition differs between brands and depends on the use time and weathering state of the material (Halsband et al, 2020;Kim et al, 2023). As mentioned above, this hampers the comparability between leachate studies and making predictions for natural ecosystems based on their results.…”

Section: Tablementioning

confidence: 99%

“…While acute toxicity of TWP leachates as well as sub-lethal effects on behavior, development, feeding, reproduction, and biomarkers have been studied in copepods, rotifers, and bivalves (Capolupo et al, 2020;Halsband et al, 2020;Lehtiniemi et al, 2021;Shin et al, 2022;Tallec et al, 2022bTallec et al, , 2022aYang et al, 2022), the number of studied invertebrate species is still limited. Adverse effects of TWP leachates or the tire-derived compound 6PPD-quinone have also been reported for several fish species, resulting in impaired eye development, changes in swimming behavior and mortality (Brinkmann et al, 2022;Chang et al, 2023;Kim et al, 2023;McIntyre et al, 2021;Tian et al, 2021). However, it has also been demonstrated that sensitivity to tire-derived additives can be highly species-specific, such as for 6PPD-quinone (Brinkmann et al, 2022;Foldvik et al, 2022;Tian et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

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Toxicity of Tire Particle Leachates on Early Life Stages of Keystone Sea Urchin Species

Rist,

Le Du-Carrée,

Ugwu

et al. 2023

Preprint

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Section: Tablementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Toxicity of Tire Particle Leachates on Early Life Stages of Keystone Sea Urchin Species

Rist,

Le Du-Carrée,

Ugwu

et al. 2023

Preprint

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“…Studies have revealed a range of adverse effects associated with BTHs; for example, chronic exposure to personal care products (PPCPs) containing BTHs can affect neuroendocrine and neuronal development in juvenile Atlantic cod [11]. BTHs in tire particle leachate can cause growth inhibition in plants, abnormal fish embryo development, and death of water fleas [12]. Wastewater containing BTHs inhibits neurite growth in SH-SY5Y cells [13], causing neurotoxicity [14], and benzothiazole ionic liquids induce acute toxicity and tissue damage in zebrafish [15].…”

Section: Introductionmentioning

confidence: 99%

Comparing the Developmental Toxicity Delay and Neurotoxicity of Benzothiazole and Its Derivatives (BTHs) in Juvenile Zebrafish

Yin,

Wang,

Mao

2024

Toxics

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In this study, a semi-static water exposure method was employed to investigate the early developmental and neurotoxic effects of four benzothiazole substances (BTHs), namely benzothiazole (BTH), 2-mercaptobenzothiazole (MBT), 2-hydroxybenzothiazole (BTON), and 2-aminobenzothiazole (2-ABTH), on zebrafish at an equimolar concentration of 10 μM. The findings revealed that all four BTHs exerted certain impacts on early development in zebrafish. MBT stimulated spontaneous movement in juvenile zebrafish, whereas BTON inhibited such movements. Moreover, all four BTHs hindered the hatching process of zebrafish larvae, with MBT exhibiting the strongest inhibition at 24 h post-fertilization (hpf). Notably, MBT acted as a melanin inhibitor by suppressing melanin production in juvenile zebrafish eyes and weakening phototaxis. Additionally, both BTH and BTON exhibited significantly lower speeds than the control group and other test groups under conditions without bright field stimulation; however, their speeds increased to average levels after percussion stimulation, indicating no significant alteration in motor ability among experimental zebrafish groups. Short-term exposure to these four types of BTHs induced oxidative damage in zebrafish larvae; specifically, BTH-, MBT-, and BTON-exposed groups displayed abnormal expression patterns of genes related to oxidative damage. Exposure to both BTH and MBT led to reduced fluorescence intensity in transgenic zebrafish labeled with central nervous system markers, suggesting inhibition of central nervous system development. Furthermore, real-time quantitative PCR results demonstrated abnormal gene expression associated with neural development. However, no significant changes were observed in 2-ABTH gene expression at this concentration. Overall findings indicate that short-term exposure to BTHs stimulates neurodevelopmental gene expression accompanied by oxidative damage.

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Biological exposure to microplastics and nanoplastics and plastic additives: impairment of glycolipid metabolism and adverse effects on metabolic diseases

Zheng,

Li,

Lai

et al. 2024

Environ Sci Pollut Res

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Chemical toxicity screening of tire particle leachates from vehicles and their effects on organisms across three trophic levels

Cited by 13 publications

References 42 publications

Toxicity of Tire Particle Leachates on Early Life Stages of Keystone Sea Urchin Species

Toxicity of Tire Particle Leachates on Early Life Stages of Keystone Sea Urchin Species

Comparing the Developmental Toxicity Delay and Neurotoxicity of Benzothiazole and Its Derivatives (BTHs) in Juvenile Zebrafish

Biological exposure to microplastics and nanoplastics and plastic additives: impairment of glycolipid metabolism and adverse effects on metabolic diseases

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