ChemInform Abstract: 1,2‐Dihydro‐2‐thioxo‐4H‐3,1‐benzothiazin‐4‐one: Formation from Carbon Disulfide and Isatoic Anhydride.

Abstract

1,2-Dihydro-2-thioxo-4H-3,1-benzothiazin-4-one: Formation from Carbon Disulfide and Isatoic Anhydride. -The reaction affords unexpectedly the benzothiazinone (III) as sole product. It can be readily methylated to give the selective inhibitor (V) of human leukocyte elastase. -(OTTERSBACH, P.; HAECKER, H.-G.; ELSINGHORST, P. W.; SCHNAKENBURG, G.; GUETSCHOW*, M.; Tetrahedron Lett. 51 (