ChemInform Abstract: 2,2,2‐Trifluoro‐1‐(1‐adamantyl)ethylamine Hydrochloride.

Abstract

bridged compoundsbridged compounds Q 0060 18 -177 2,2,2-Trifluoro-1-(1-adamantyl)ethylamine Hydrochloride.-1-Adamantyl trifluoromethyl ketone (III), prepared by coupling of 1adamantylmagnesium bromide (I) with trifluoroacetyl chloride (II), reacts with hydroxylamine-O-sulfonic acid to form the oxime (IV). Reduction of (IV) with lithium aluminum hydride followed by treatment with hydrochloric acid yields the title compound (V). -(YURCHENKO, A. G.; FEDORENKO, T. V.; TIKCHONOV, V. P.; SOLOSHONOK, V. A.; KUKHAR', V. P.; J.