ChemInform Abstract: 4‐Ketoantheraxanthin, a Novel Carotenoid Produced by the Combination of the Bacterial Enzyme β‐Carotene Ketolase CrtW and Endogenous Carotenoid Biosynthetic Enzymes in Higher Plants.

Abstract

Terpenes U 0200 4-Ketoantheraxanthin, a Novel Carotenoid Produced by the Combination of the Bacterial Enzyme β-Carotene Ketolase CrtW and Endogenous Carotenoid Biosynthetic Enzymes in Higher Plants. -The title compound exhibits potent antioxidative activity, presumably due to its C4-keto function. -(SHINDO*, K.; HASUNUMA, T.; ASAGI, E.; SANO, A.; HOTTA, E.; MINEMURA, N.; MIYAKE, C.; MAOKA, T.; MISAWA, N.; Tetrahedron Lett. 49 (2008) 20, 3294-3296; Dep. Food Nutr., Japan Women's Univ., Bunkyo, Tokyo 112, Japan; Eng.) -R. Simon 35-171

Molecular Breeding of Sweetpotato Carotenoids

“…Through pathway engineering that utilizes the marine bacterial carotenoid 4,4′-ketolase (4,4′-oxygenase) gene named c r t W, unique keto-carotenoids such as astaxanthindiglucoside, 2,2′-dihydroxyastaxanthin, and 2,2′-dihydroxycanthaxanthin have been produced in Escherichia coli [146,147] and 4-ketoantheraxanthin in tobacco (Nicotiana tabacum) plants [148]. Breitenbach et al [149] also synthesized α-echinenone (4-keto-α-carotene) in rice callus using crtW.…”

“…Molecular Breeding of Sweetpotato Carotenoids DOI: http://dx.doi.org/10.5772/intechopen.101849 was assumed that the new structural carotenoids with epoxy and keto groups can be produced by expressing the ketolase crtW gene in sweetpotato tubers. Recently, marine bacterial genes that include the crtW gene encoding carotenoid 4,4′-ketolase [148] was introduced into sweetpotato cultivar W71 under the control of the CaMV promoter. Consequently, novel carotenoids with epoxy and keto groups 1, 2, and 3 were obtained along with a series of ketocarotenoids.…”