ChemInform Abstract: 5‐FLUOR‐5‐ALKYL(ARYL)BARBITURSAEUREN

Partially fluorinated heterocyclic compounds. Part 22. The preparation of allyl 2,5,6-trifluoropyrimidin-4-yl ether and related compounds and a study of their Claisen rearrangement reactions. A new route to 5-fluorouracil and barbituric acid derivatives

“…Compound (31) was evaporated at 25 "C/12 mmHg and the residue was distilled to give dimethyl 2-allyl-2-jZuoropropanedioate (32)(1.43 g, 26%), b.p. 105-110 "(712 mmHg(Found: C, 50.75; H,6.15%; M ' , 190. CsHl,FO, requires C, 50.52; H, 5.83%; M, 190); SdCDCl,) 166.2 p.p.m.…”

“…We have also prepared and thermolysed two other allyl pyrimidinyl ethers (5) and (6). Reaction of (1) with 1 mol equiv.…”