ChemInform
 2012
DOI: 10.1002/chin.201220169
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ChemInform Abstract: 6‐Alkynylpurines Bearing Electronacceptor Substituents: Preparation, Reactivity in Cycloaddition Reactions and Cytostatic Activity.

Martin Krovacek
1
,
Hana Dvořáková
2
,
Ivan Votruba
3
et al.

Abstract: While direct Sonogashira coupling of 6‐halopurines (I) with propargyl aldehyde or methyl propiolate fails, the corresponding diethyl acetal (IIa) and orthoester (IIb) react smoothly.

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