ChemInform Abstract: A Highly Efficient Route to Dehydroalanine Containing Peptides.

Abstract

A Highly Efficient Route to Dehydroalanine Containing Peptides.-A general method for the synthesis of dehydroalanine-containing peptides is reported. The structural element is introduced as S-methyl cystein and subsequently liberated by oxidation and elimination. The procedure is compatible with usual protecting groups Boc and Fmoc. -(BURRAGE, S. A.; RAYNHAM, T.; BRADLEY, M.; Tetrahedron Lett. 39 (1998) 18, 2831-2834 Dep. Chem., Univ. Southampton, Southampton SO17 1BJ, UK; EN)