ChemInform Abstract: A Parham Cyclization Approach to Diaryl‐Fused Seven‐Membered Ring Heterocyclic Ketones.

Abstract

A Parham Cyclization Approach to Diaryl-Fused Seven-Membered Ring Heterocyclic Ketones. -The novel synthesis of the title compounds involves the generation of functionalized aryllithiums from aryl bromides followed by intramolecular cyclization onto an electrophilic nitrile functional group. -(FARROKH, J.; CAMPOS, C.; HUNT*, D. A.; Tetrahedron Lett. 56 (2015) 37, 5245-5247, http://dx.