ChemInform Abstract: A “Turn‐on” Coumarin‐Based Fluorescent Sensor with High Selectivity for Mercury Ions in Aqueous Media

Voutsadaki, Styliani; Tsikalas, George K.; Klontzas, Emmanuel; Froudakis, George E.; Katerinopoulos, Haralambos E.

doi:10.1002/chin.201035144

Cited by 1 publication

(1 citation statement)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most fluorescent probes achieve detection by the “turn‐off” mechanism. However, other factors such as concentration or temperatures variation may lead to fluorescence quenching in the solution, leading to low reliability . The “turn‐on” system provides a different alternative which intuitively shows the existence of substances through fluorescence intensity changes .…”

Section: Introductionmentioning

confidence: 99%

An Enzyme‐Responsive “Turn‐on” Fluorescence Polymeric Superamphiphile as a Potential Visualizable Phosphate Prodrug Delivery Vehicle

Yang

Shen

Guo

et al. 2018

Macromolecular Bioscience

View full text Add to dashboard Cite

The development of inexpensive and highly efficient enzyme-responsive polymers has significantly contributed to targeted drug delivery systems. Here, a superamphiphile with a capability of fluorescent dissociation sensing is designed. It is constructed with negatively charged adenosine 5'-triphosphate (ATP) and negatively charged fluorescein diphosphate (FDP), which are used as fluorescence detection, and a cationic diblock copolymer methoxy-poly(ethylene glycol) -b-poly(2-dimethyl-aminoethyl methacrylate) . Upon addition of calf intestinal alkaline phosphatase, the superamphiphile disintegrates, presumably due to the enzymatic hydrolysis of ATP. This process is accompanied by an increase in the fluorescence emission intensity of fluorescein owing to the hydrolysis of FDP. The in vitro application of the superamphiphile is also proven. Thus, the "turn-on" fluorescence of the superamphiphile serves as a real-time module for detection of the disintegration of superamphiphile.

show abstract

Section: Introductionmentioning

confidence: 99%

An Enzyme‐Responsive “Turn‐on” Fluorescence Polymeric Superamphiphile as a Potential Visualizable Phosphate Prodrug Delivery Vehicle

Yang

Shen

Guo

et al. 2018

Macromolecular Bioscience

View full text Add to dashboard Cite

show abstract

ChemInform Abstract: A “Turn‐on” Coumarin‐Based Fluorescent Sensor with High Selectivity for Mercury Ions in Aqueous Media

Abstract: Media -[synthesis and spectral profile of (I)]. -(VOUTSADAKI, S.; TSIKALAS, G. K.; KLONTZAS, E.; FROUDAKIS, G. E.; KATERINOPOULOS, H. E.; Chem.

Cited by 1 publication

References 1 publication

An Enzyme‐Responsive “Turn‐on” Fluorescence Polymeric Superamphiphile as a Potential Visualizable Phosphate Prodrug Delivery Vehicle

An Enzyme‐Responsive “Turn‐on” Fluorescence Polymeric Superamphiphile as a Potential Visualizable Phosphate Prodrug Delivery Vehicle

Contact Info

Product

Resources

About