ChemInform Abstract: Amberlyst‐15 Catalyzed Povarov Reaction of N‐Arylidene‐1H‐indazol‐6‐amines and Indoles: A Greener Approach to the Synthesis of exo‐1,6,7,7a,12,12a‐Hexahydroindolo[3,2‐c]pyrazolo[3,4‐f]quinolines as Potential Sirtuin Inhibitors.

Abstract

Interestingly, compounds (IV) derived from 5‐bromoindole (II) exhibit a higher degree of Sir‐2 inhibition as compared to their counterparts, derived from indole.