ChemInform Abstract: Antinociceptive Pyrimidine Derivatives: Aqueous Multicomponent Microwave‐Assisted Synthesis.

Abstract

Phenylamidine hydrochloride reacts with either ethyl cyanoacetate or malononitrile and aromatic aldehydes to provide the access to small libraries of pyrimidine derivatives and their oxo analogues, some of which show antinociceptive activity.