ChemInform Abstract: Applications of Metal Complexes of Schiff Bases

Kumar, Shalin; Dhar, D. N.; Saxena, Pushplata

doi:10.1002/chin.201026226

Cited by 97 publications

(97 citation statements)

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“…Metal complexes of Schiff base ligands possess a variety of applications in the biological, analytical, clinical, and industrial areas [1]. In recent times, transition metal complexes of Schiff base ligands have gained considerable attention, not only due to their spectroscopic properties and applications [2] but also due to their remarkable antifungal, antibacterial and antitumor activities [3].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Antibacterial Studies of Metal Complexes of Cu(II), Ni(II) and Co(II) with Tetradentate Ligand

Abdulkarem¹

2017

JBPC

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The new metal complexes of Cu(II), Ni(II) and Co(II) with the new ligand derived from isatine and 1,2-diaminocyclohexane were synthesized and biologically screened. The synthesized complexes and ligand were characterized by spectroscopic FT-IR, UV-VIS, 1 H-NMR and elemental analyses. The ligand and complexes were screened for their antibacterial activities against three different strains, namely E. coli, P. aeruginosa and S. aureus. In particular, the Co(II) and Cu-complexes exhibited excellent antibacterial activities compared to the reference compound.

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Section: Introductionmentioning

confidence: 99%

Synthesis and Antibacterial Studies of Metal Complexes of Cu(II), Ni(II) and Co(II) with Tetradentate Ligand

Abdulkarem¹

2017

JBPC

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“…They often display liquid crystalline (LC) behavior at room temperature as well as ability to form chelates with metals. [1][2][3][4][5][6][7][8] As a consequence, PAMs have a potential for numerous application in electronics, optoelectronics, photonics, and sensors. [6][7][8] PAMs can be synthesized in a traditional approach (also known as polyazomethine route) by a reaction of dialdehydes with diamines.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of fluorinated poly(azomethine ether)s from new core-fluorinated azomethine-containing monomers

Kobzar

Ткаченко

Bliznyuk

et al. 2015

Designed Monomers and Polymers

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In this work, we describe the design and synthesis of novel core-fluorinated Schiff base monomers and conjugated polymers based on them. The new fully aromatic highly fluorinated poly(azomethine ether)s (PAMEs) were prepared by polycondensation of core-fluorinated azomethine-containing compounds. The structure of the monomers and polymers were confirmed by FTIR, F NMR spectroscopic analysis. The influence of synthesis condition on the properties of PAME compounds was investigated. Application of polarization microscopy with a temperature control thermal stage revealed thermotropic liquid crystalline (LC) behavior in the synthesized materials. Transition temperatures and a range of the existence of the LC phase were studied by a combination of the optical microscopy and DSC analysis. According to the TGA analysis, all the synthesized PAMEs show high thermal stability and thus offer a wide range of thermal processibility (up to 410-477 °C), which makes them prospective materials for many modern applications.

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“…Hydrazone ligands (HL) possessing potential donor sites that have coordination capability exhibit biological activities that may be due to the presence of the azomethine and the uncoordinated a-nitrogen of the hydrazone chromosphere. This coordination capability has led to research on the synthesis of metal complexes of new hydrazones with significant biological activity [4][5][6] . One of the most important goals of pharmacological research is the search for new molecular structures which exhibit effective antitumor activities.…”

Section: Introductionmentioning

confidence: 99%

Synthesis andin vitrobiological evaluation of new heterocycles based on the indole moiety

Kandile

Mohamed

Ismaeel

2014

Journal of Enzyme Inhibition and Medicinal Chemistry

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New compounds based on the indole moiety were synthesized via the reaction of indole-3-carbinal 1 with different nucleophiles such as 6-aryl-[4-(2-methoxybenzyl)pyridazin-3-yl] hydrazones 2a-c, benzidine, 3,3 0 -dimethoxybenzidine 4a,b and 2,6-diaminopyridine 6 to afford hydrazine derivatives 3a-c and three different classes of bis-Schiff bases. The structures of the new compounds were elucidated on the basis of their FTIR, 1 H NMR, 13C NMR spectral data, GC/MS and elemental analysis. The antimicrobial activity of the new compounds was evaluated using a broth dilution technique in terms of minimal inhibitory concentration (MIC) against four pathogenic bacteria and two pathogenic fungi strains. Compound 14b showed excellent activity against Escherichia coli and Klebsiella pneumoniae. Some of the prepared compounds were tested for anti-cancer activity against human cell lines HCT116 (colon), MCF7 (breast) and HELA (cervix). From the results of the in vitro assays, compounds 3a,b, and 18a,c presented promising anti-cancer activity.

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ChemInform Abstract: Applications of Metal Complexes of Schiff Bases

Cited by 97 publications

References 0 publications

Synthesis and Antibacterial Studies of Metal Complexes of Cu(II), Ni(II) and Co(II) with Tetradentate Ligand

Synthesis and Antibacterial Studies of Metal Complexes of Cu(II), Ni(II) and Co(II) with Tetradentate Ligand

Synthesis and characterization of fluorinated poly(azomethine ether)s from new core-fluorinated azomethine-containing monomers

Synthesis andin vitrobiological evaluation of new heterocycles based on the indole moiety

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