ChemInform Abstract: Asymmetric Aldol Reactions Between Acetone and Benzaldehydes Catalyzed by Chiral Zn²⁺ Complexes of Aminoacyl 1,4,7,10‐Tetraazacyclododecane: Fine‐Tuning of the Amino‐Acid Side Chains and a Revised Reaction Mechanism.

Abstract

Asymmetric Aldol Reactions Between Acetone and Benzaldehydes Catalyzed by Chiral Zn 2+ Complexes of Aminoacyl 1,4,7,10-Tetraazacyclododecane: Fine-Tuning of the Amino-Acid Side Chains and a Revised Reaction Mechanism. -The yields and enantioselectivities of the reaction are improved compared to the known methods. The reaction mechanism is discussed and the previously proposed mechanism is corrected. -(ITOH, S.; TOKUNAGA, T.; SONOIKE, S.; KITAMURA, M.; YAMANO, A.; AOKI*, S.; Chem. -Asian J. 8 (2013) 9, 2125-2135, http://dx.