ChemInform Abstract: Asymmetric Deprotonation and Complexation Reactions Mediated by Chiral Ketals as a Route to Ortho‐Disubstituted (η6‐Arene)Cr(CO)3 Complexes.

Abstract

1992organo-chromium compounds organo-chromium compounds S 5500 -224Asymmetric Deprotonation and Complexation Reactions Mediated by Chiral Ketals as a Route to Ortho-Disubstituted (η6-Arene)Cr(CO)3 Complexes.-Deprotonation of the chiral chromium complexes (I) with tert-butyllithium followed by treatment with the electrophiles (II) yields diastereoselectively the ortho-substituted complexes (III) as the main products. In contrast, complexation of the ortho-disubstituted benzenes (V) with chromiumhexacarbonyl (VI) proceeds with a much lower diastereoselectivity or none. -(AUBE, J.; HEPPERT, J. A.; MILLIGAN, M. L.; SMITH, M. J.; ZENK, P.; J.