ChemInform Abstract: Asymmetric Diels‐Alder Reactions: EPC‐Synthesis of a Stable Sarkomycin Precursor.

Abstract

The key step in the synthesis of the cyclosarkomycin (IX) is the stereoselective Diels‐Alder reaction of the chiral bromoacrylate (Ia) with cyclopentadiene (II) to form mainly the cycloadduct (IIIa).