ChemInform Abstract: Bi(OTf)₃‐Catalyzed One‐Step Catalytic Synthesis of N‐Boc or N‐Cbz Protected α‐Branched Amines.

Abstract

Bi(OTf) 3-Catalyzed One-Step Catalytic Synthesis of N-Boc or N-Cbz Protected -Branched Amines. -A one-pot, three-component aza-Friedel-Crafts reaction of electron-rich arenes with a variety of aldehydes and tert-butyl or benzyl carbamate provides an efficient method for preparation of N-protected -branched amines. -(JARATJAROONPHONG*, J.; TUENGPANYA, S.; RUENGSANGTONGKUL, S.; J. Org. Chem. 80 (2015) 1, 559-567, http://dx.