ChemInform Abstract: Bone Selective Effect of an Estradiol Conjugate with a Novel Tetracycline‐Derived Bone‐Targeting Agent.

Neale, Jason; Richter, Natali B.; Merten, Kevyn E.; Taylor, K. Grant; Singh, Sujan; Waite, Leonard C.; Emery, Nicole K.; Smith, Ned B.; Cai, Jian; Pierce, William M.

doi:10.1002/chin.200925180

Cited by 1 publication

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“…Nevertheless, taking account of the side effects, there is no application of tetracycline derivatives in bone tumors. There are other bone-targeting ligands that can be potentially applied to bone cancer imaging (e.g., succinic acid) (Neale et al, 2009). In addition, a variety of carboxylate-containing ligands or polymers can also deliver the bone-targeting feature to the probes.…”

Section: Fluorescence Probes With Targeting Bone Characteristic Synthesismentioning

confidence: 99%

Precise Diagnosis and Therapy of Bone Cancer Using Near-Infrared Lights

Cai

et al. 2021

Front. Bioeng. Biotechnol.

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Bone is a preferred site for both primary and metastasis tumors. Current diagnosis of osteopathia typically relies on noninvasive skeleton radiography technology. However, due to the limited resolution of ionizing radiation, accurate diagnosis and effective identification impairment areas are still lacking. Near-infrared (NIR) bioimaging, especially in the NIR-II (1000-1700 nm) regions, can provide high sensitivity and spatiotemporal resolution bioimaging compared to the conventional radiography. Thus, NIR bioimaging affords intraoperative visualization and imaging-guided surgery, aiming to overcome challenges associated with theranostics of osteopathia and bone tumors. The present review aimed to summarize the latest evidence on the use of NIR probes for the targeting bone imaging. We further highlight the recent advances in bone photoX (X presents thermal, dynamic, and immuno) therapy through NIR probes, in particular combination with other customized therapeutic agents could provide high-efficiency treatment for bone tumors.

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Section: Fluorescence Probes With Targeting Bone Characteristic Synthesismentioning

confidence: 99%

Precise Diagnosis and Therapy of Bone Cancer Using Near-Infrared Lights

Cai

et al. 2021

Front. Bioeng. Biotechnol.

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ChemInform Abstract: Bone Selective Effect of an Estradiol Conjugate with a Novel Tetracycline‐Derived Bone‐Targeting Agent.

Cited by 1 publication

References 1 publication

Precise Diagnosis and Therapy of Bone Cancer Using Near-Infrared Lights

Precise Diagnosis and Therapy of Bone Cancer Using Near-Infrared Lights

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