ChemInform Abstract: Bromination of Pyridines. Part 2. Bromination of Aminopicolines.

Abstract

ChemInform Abstract The bromination of all ten possible aminopicolines is investigated using 48% HBr/H2O2 at 70 rc C. In general, the major product is that corresponding to electrophilic attack at the sites para or ortho to the amino group. The aminobromopicolines are required for pharmaceutical and agrochemical screening.