ChemInform Abstract: Chemoselective Hydration of Glycosyl Cyanides to C‐Glycosyl Formamides Using Ruthenium Complexes in Aqueous Media.

Abstract

Media. -A wide variety of glycosyl cyanides such as (I) are converted into the corresponding formamide derivatives in water or water/NMP mixtures as the solvent. O-Acetyl, O-benzoyl, O-benzyl protecting groups, double bonds, anomeric bromide, and azide substituents are compatible to this reaction conditions. -(MISRA, A. K.; BOKOR, E.; KUN, S.; BOLYOG-NAGY, E.; KATHO, A.; JOO, F.; SOMSAK*, L.; Tetrahedron Lett. 56 (2015) 44, 5995-5998, http://dx.