ChemInform Abstract: Cu(I)—NHC‐Catalyzed Silylation of Allenes: Diastereoselective Three‐Component Coupling with Aldehydes.

Abstract

Cu(I)-NHC-Catalyzed Silylation of Allenes: Diastereoselective Three-Component Coupling with Aldehydes. -The highly regioselective copper-catalyzed reaction of aryl allenes with silylborane (II) affords vinyl silane building blocks. The reaction can be extended to give homoallylic alcohols with high diastereoselectivity upon replacing MeOH with an aldehyde. -(RAE, J.; HU, Y. C.; PROCTER*, D. J.; Chem. -Eur. J. 20 (2014) 41, 13143-13145, http://dx.doi.org/10.1002/chem.201404330 ; Sch. Chem., Univ. Manchester, Manchester M13 9PL, UK; Eng.) -Mais 14-245