ChemInform Abstract: Cyclic Oxalylation of Primary N‐Substituted Anthranilamides: 1H‐Benzo[e][1,4]diazepine‐2,3,5(4H)‐triones and 11a‐Chlorobenzo[e]oxazolo[3,2‐a] [1,4]diazepine‐2,3,5,11(10H,11aH)‐tetraones.

Abstract

Reaction of primary anthranilamide (I) with oxalyl chloride in the presence of imidazole gives selectively the title benzodiazepine (III) or benzoxazolodiazepine derivatives (IV) depending on the molar ratio of the reactants.