ChemInform Abstract: Cyclization of N‐(2‐Hydroxyethyl)‐N‐phenylmethyl‐N′‐substituted Ureas and Thioureas: Prelude to the Synthesis of 1‐Aryl‐substituted‐2‐imidazolidinones on Solid Support.

Abstract

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Classical and Microwave-Assisted Synthesis of Substituted-Dihydroxy-imidazolidine-2-thiones Compounds

“…Thiourea derivatives has attracted interest due to their potential use as reagents for the separation of metal ions [7][8][9] and in biological applications for example; antibacterial [3,8,10,11], antiviral [7] antifungal agents [7,8,[12][13][14]. And thioureas have recently taken attention as protease inhibitors of human immunodeficiency virus (HIV) [3,15,16]. Some thiourea derivatives has in vivo and in vitro activity and parasitic worms [14,17].…”

“…And thioureas have recently taken attention as protease inhibitors of human immunodeficiency virus (HIV) [3,15,16].…”