ChemInform Abstract: Derivatives of 4H‐Pyran‐4‐one with the Atom of Sulfur in the Side Chain.

Abstract

Derivatives of 4H-Pyran-4-one with the Atom of Sulfur in the Side Chain.-[synthesis and biological evaluation of sulfur-containing derivatives of kojic acid such as (III), (IV), and (VIII)]. -(UHER, M.; KYSELICOVA, L.; RAJNIAKOVA, O.; HUDECOVA, D.; BRANSOVA, J.; BRTKO, J.; Chem.

Biological functions of kojic acid and its derivatives in medicine, cosmetics, and food industry: Insights into health aspects

“…[37][38][39][40] Moreover, several sulfurcontaining kojic acid derivatives were proven to exert potent antifungal activity. [41] An improvement in the antifungal activity of kojic acid derivatives can be acquired by enhancing the hydrophobicity of the compounds. [13] Novel acrylate monomers, based on kojic acid derivatives, have also shown both antibacterial and antifungal activities.…”

Synthesis and Some Properties of New 5-Hydroxy-2-[(hetarylthio)methyl]-4H-pyran-4-ones

“…One of the most accessible methods of functionalization of kojic acid is its transformation into bromo-or chlorokojic acid 11, with further replacement of the halogen atom by various nucleophiles such as thioureas [28][29][30][31][32][33], alkyl mercaptans [29,30,34], thiophenols [21,35], sodium arylsulfinates [36], alkali metal thiocyanates [36][37][38][39], S-glycosylisothiuronium salts [40], various mercaptoazoles [22,25,28,29,41], 2-mercaptopyrimidines [24,42], 2-mercaptoquinazolines [43,44], mono-and dithiophosphates [45,46]. Many of the compounds obtained in this way are of interest for agrochemistry as growth regulators and herbicides comparable in efficiency to Fluazifop-P [29], or as insecticides [45,46].…”