ChemInform Abstract: Diastereoselective Alkylation of 3‐Acylimidazolidin‐2‐ones: Synthesis of (R)‐ and (S)‐Lavandulol.

Abstract

Acylation of the lithium salt of the (4R,5S)‐imidazolidinone (I) with the acyl chloride (II) gives the compound (III) which is alkylated with the alkenyl bromide (IV) to yield (V).