ChemInform Abstract: Diastereoselective Synthesis of 2,6‐Diaryltetrahydrothiopyran‐4‐ones by Phase‐Transfer Catalysis.

Abstract

Diastereoselective Synthesis of 2,6-Diaryltetrahydrothiopyran-4-ones by Phase-Transfer Catalysis. -Two efficient phase-transfer-catalyzed protocols for the diastereoselective synthesis of cis and trans isomers of 2,6-diaryltetrahydrothiopyran-4-ones (2,6-DATHTPs) are developed. In a study of the scope of the reactions, differently substituted 2,6-DATHTPs are accessed in high yields and diastereomeric excesses on both experimental and preparative scales. -(GENDRON, T.; KESSEDJIAN, H.; DAVIOUD-CHARVET, E.; LANFRANCHI*, D. A.; Eur.