ChemInform Abstract: Diastereoselective Synthesis of Tetrasubstituted Propargylamines via Hydroamination and Metalation of 1‐Alkynes and Their Enantioselective Conversion to Trisubstituted Chiral Allenes.
Abstract:The reactions involve the diastereoselective addition of in situ formed alkynylcopper complexes to in situ formed iminium ions regioselectively affording the corresponding propargylamines.
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