ChemInform Abstract: DIOXOPYRROLINES. XXVII. SYNTHESES OF 2‐ARYL‐3‐ETHOXYCARBONYL‐ Δ2‐PYRROLINE‐4,5‐DIONES

Sano, Takehiro; Horiguchi, Yuji; Toda, Jun; Imafuku, K.; Tsuda, Yoshisuke

doi:10.1002/chin.198433172

Cited by 1 publication

(1 citation statement)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the reaction of substituted 4,5‐dihydro‐1 H ‐pyrroles 292 [283] with arylaminodimethylcyclohexenones 293 in a 1 : 1 molar ratio in boiling anhydrous m ‐xylene, the corresponding spiro‐fused pyrrolo‐tetrahydroacridinones 294 were synthesized in good yields. Presumably, compounds 294 are formed through initial nucleophilic addition of the activated ortho ‐carbon atom in the arylamino group of cyclic enamine 293 to the C(4) carbonyl atom of the pyrrole ring in 292 .…”

Section: Synthesis Of Spirocyclic Quinoxaline Acridine Benzoxazinementioning

confidence: 99%

Advances in the Synthesis of Benzo‐Fused Spiro Nitrogen Heterocycles: New Approaches and Modification of Old Strategies

Гатауллин

2020

Helvetica Chimica Acta

View full text Add to dashboard Cite

The review covers the results of studies published in the literature on the synthesis of spiro-linked heterocycles of the indole, quinoline, benzoxazine, benzothiazine, indenoquinoxaline, pyridopyrimidine, and acridine series. Possible approaches to the synthesis of spirocycles through a sequence of well-known Knoevenagel, Michael reactions, deamination cyclization of 1,2-dicarbonyl, CH-acid compounds, direct cycloaddition of activated olefins to isatins, 3-alkylideneindoles, 2-oxindoles, in situ generated azomethine ylides, indenoquinoxalines are analyzed. Attention is drawn to approaches to the preparation of spiro-fused compounds using reactions of intra-and intermolecular dearomatization of indoles. Recent advances in the synthesis of spiro-linked benzo heterocycles from derivatives of 2-olefin substituted anilines are summarized. The examples of the synthesis of spiro-fused heterocycles by means of metal complexes catalyzed decomposition of diazo compounds are given. Some syntheses of biologically active representatives are shown, as well as the use of transformations of spiroheterocycles in the preparation of other heterocycles.

show abstract

Section: Synthesis Of Spirocyclic Quinoxaline Acridine Benzoxazinementioning

confidence: 99%

Advances in the Synthesis of Benzo‐Fused Spiro Nitrogen Heterocycles: New Approaches and Modification of Old Strategies

Гатауллин

2020

Helvetica Chimica Acta

View full text Add to dashboard Cite

show abstract

ChemInform Abstract: DIOXOPYRROLINES. XXVII. SYNTHESES OF 2‐ARYL‐3‐ETHOXYCARBONYL‐ Δ2‐PYRROLINE‐4,5‐DIONES

Abstract: Die aus β‐Ketoestern (I) durch Umsetzung mit Aminen (II) in Essigsäure hergestellten Enaminoester (III) cyclisieren mit Oxalylchlorid (IV) zu Dioxopyrroli‐ nen (V).

Cited by 1 publication

References 1 publication

Advances in the Synthesis of Benzo‐Fused Spiro Nitrogen Heterocycles: New Approaches and Modification of Old Strategies

Advances in the Synthesis of Benzo‐Fused Spiro Nitrogen Heterocycles: New Approaches and Modification of Old Strategies

Contact Info

Product

Resources

About