ChemInform Abstract: Domino Reaction of α‐Acetyl‐α‐carbamoyl Ketene Dithioacetals with Vilsmeier Reagents: A Novel and Efficient Synthesis of 4‐Halogenated 2(1H)‐Pyridinones.

Abstract

Synthesis of 4-Halogenated 2(1H)-Pyridinones. -The target compounds are useful synthons which can easily be transformed into biologically important diazepines such as (XI) and some other products. Starting from dithioacetals of type (IV), diones are formed instead of the expected halogenated pyridinones. -(CHEN, L.; ZHAO*, Y.-L.; LIU, Q.; CHENG, C.; PIAO, C.-R.; J. Org. Chem. 72 (2007) 24, 9259-9263; Dep. Chem., Northeast Norm. Univ., Changchun 130024, Peop. Rep. China; Eng.) -Jannicke 15-138