ChemInform Abstract: Efficient Preparation of the Key Intermediate in Corey′s Tamiflu Synthesis.

Abstract

Efficient Preparation of the Key Intermediate in Corey's Tamiflu Synthesis. -The simple two-step synthesis of the compounds (VI) which starts from easily available material and may be practical for large-scale preparations affords the title intermediate (VIc). A more facile synthesis of (VI) is also investigated but is less effective for (VIc).-(HONG*, Z.; CUI, Q.; PENG, J.; HU, H.; CHEN, Z.; Chin.