ChemInform Abstract: Enantioselective Hydrogenation of Functionalized Ketones. Synthesis and Application of New Chiral Aminophosphine‐Phosphinite Ligands.

Abstract

1999 stereochemistry stereochemistry (general, optical resolution) O 0030 04 -041 Enantioselective Hydrogenation of Functionalized Ketones. Synthesis and Application of New Chiral Aminophosphine-Phosphinite Ligands. -New chiral aminophosphine-phosphinites such as (I) are easily obtained by coupling of chiral amino alcohols with chlorophosphines. They are successfully applied to enantioselective hydrogenation of derivatives of α-ketocarboxylic acids. -(PASQUIER, C.; EILERS, J.; REINERS, I.; MARTENS, J.; MORTREUX, A.; AGBOSSOU, F.; Synlett (1998) 10, 1162-1164; Lab. Catal.