ChemInform Abstract: Flavonol Glycosides and Iridoids from Asperula lilaciflora

Abstract

A new flavonol glycoside, quercetin 3-O-[6'''-O-3,5-dihydroxycinnamoyl-b-glucopyranosyl-(1 ! 2)]-b-galactopyranoside (named lilacifloroside; 1) and a new iridoid 2 (named asperulogenin), were isolated from the aerial parts of Asperula lilaciflora in addition to eight known secondary metabolites, i.e., quercetin, kaempferol, quercetin 3-O-b-glucopyranosyl-(1 ! 2)-b-galactopyranoside, quercetin 3-O-bglucopyranosyl-(1 ! 2)-arabinopyranoside, asperuloside, deacetylasperulosidic acid, asperulosidic acid methyl ester, and chlorogenic acid. The structures were elucidated on the basis of extensive 1D-and 2D-NMR experiments as well as MS data. Compound 1 contains the rare 3,5-dihydroxycinnamoyl moiety in its structure. This work constitutes the first phytochemical study of the title plant.

Evaluation of hplc, phytochemical, anticholinesterase and antioxidant profiles of the aerial parts of asperula taurina subsp. caucasica

“…caucasica [12]. Other phytochemical studies have shown that Asperula species also contains iridoid glycosides (involucratosides A-C, adoxoside), flavone glycosides (apigenin 7-O-β-glucopyranoside, luteolin 7-Oβ-glucopyranoside, apigenin 7-O-rutinoside, lilacifloroside, quercetin, kaempferol, quercetin 3-O-βglucopyranosyl-(1→2)-β-galactopyranoside, quercetin 3-O-β-glucopyranosyl-(1→2)arabinopyranoside) and phenolic acid derivatives (chlorogenic acid and ferulic acid 4-O-βglucopyranoside) [13,14]. Some previous studies have shown that some Asperula species have antihypoxic and potent sedative, antioxidant activity [15,16].…”