ChemInform Abstract: “Halex” Fluorination of Chlorinated Benzaldehydes and Benzoyl Chlorides.

Abstract

106ChemInform Abstract Spray-dried potassium fluoride suspended in sulfolane proved to be the best system for the halogen exchange reaction of chlorinated benzaldehydes such as (I) and benzoyl chlorides such as (III) and (V). Other examples are given.

Correlation of the Rates of Solvolysis of Benzoyl Fluoride and a Consideration of Leaving-Group Effects

“…Benzoyl fluoride was the third compound with a carbon−fluorine bond to be synthesized and the first to be prepared by the halide-exchange route . It has been the subject of several kinetic investigations, mainly involving solvolysis − or aminolysis. − The solvolyses (eq 1) are subject to catalysis by added strong acids and, with relatively high substrate concentrations, autocatalysis has also been observed.…”