ChemInform Abstract: Helical Phosphorus Derivatives: Synthesis and Applications

Abstract

Review: 81 refs.

Rational Design and Synthesis of [5]Helicene-Derived Phosphine Ligands and Their Application in Pd-Catalyzed Asymmetric Reactions

“…Thus, helicenes can be utilized them a broad range of applications in chiral materials, in the chiral recognition of biomolecules, and in asymmetric synthesis161718192021222324. More specifically, chiral helicene-based trivalent phosphorus ligands are efficient asymmetric inductors in metal-catalyzed asymmetric reactions and show good to excellent enantioselectivities252627282930313233. We hypothesized that novel helicenylphosphine ligands, which induce intramolecular metal-arene interactions, could be used to construct an efficient chiral catalytic system.…”