1983
DOI: 10.1002/chin.198333165
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ChemInform Abstract: HIGH PRESSURE SYNTHESIS OF DIPHENYLAMINE FROM ANILINE AND PHENOL

Abstract: Die Abhängigkeit der Umsetzung von Phenol (I) und Anilin (II) zu Diphenylumin (III) von Katalysatoren wie Mineralsäuren und Lewissiiuren sowie von Druck, Temperatur und Verweilzeit wird untersucht.

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“…The safety profile of Nitrobenzene and aniline are improved compared to benzene, under hood and protective gear (gloves and safety glasses), hence why they were chosen. (2)(3)(4)(5) CONCLUSION Two synthetic approaches were discussed that may lead to the synthesis of novel phenothiazine derivatives which could be firstly tested through in vitro studies, and then hypothetically promise a future for therapeutic activity against prion disease with the M129 mutation. This approach could also serve for other prion mutations and ampler Prion Disease.…”
Section: Industrial Semi-synthesismentioning
confidence: 99%
“…The safety profile of Nitrobenzene and aniline are improved compared to benzene, under hood and protective gear (gloves and safety glasses), hence why they were chosen. (2)(3)(4)(5) CONCLUSION Two synthetic approaches were discussed that may lead to the synthesis of novel phenothiazine derivatives which could be firstly tested through in vitro studies, and then hypothetically promise a future for therapeutic activity against prion disease with the M129 mutation. This approach could also serve for other prion mutations and ampler Prion Disease.…”
Section: Industrial Semi-synthesismentioning
confidence: 99%