ChemInform Abstract: HOBt×DCHA‐Mediated Synthesis of Sterically Hindered Peptides Employing Fmoc‐Amino Acid Chlorides in Both Solution‐Phase and Solid Phase Methods.

Abstract

Peptides U 0400HOBt·DCHA-Mediated Synthesis of Sterically Hindered Peptides Employing Fmoc-Amino Acid Chlorides in Both Solution-Phase and Solid Phase Methods. -The coupling is complete in about 30 minutes and free of racemization. The synthesis of β-casomorphin using a solid-phase protocol on Wang resin is also presented. -(SURESHBABU*, V. V.; SUDARSHAN, N. S.; KRISHNA, G. C.; Synth. Commun. 38 (2008) 15, 2625-2637; Dep. Stud. Chem., Cent. Coll., Bangalore Univ., Bangalore 560 001, India; Eng.) -K. Woydowski 52-189