ChemInform Abstract: Host‐Guest Complexation. Part 46. Cavitands as Open Molecular Vessels Form Solvates.

Abstract

The preparation of a series of cavitands possessing four (→ (V)) or three (→ (VI)) polymethylene bridges is described; most of them are synthesized by a route similar to that shown for (Va).

Interaction of mucin with viologen and acetate derivatives of calix[4]resorcinols

“…Similar to calix [4]resorcinols, calix [4]resorcinol cavitands have a molecular cavity formed by four aromatic resorcinol moieties, but they are more conformationally rigid due to the bridging of oxygen atoms of the adjacent aromatic rings. 12 For the modification of mucoadhesive systems, cyclodextrins are sometimes used as drug delivery systems. 13 Encapsulation of hydrophobic drugs in the cavity of cyclodextrins allows preparing water-soluble dosage forms, which favorably affects the therapeutic effect.…”