ChemInform Abstract: INTERACTION OF 1‐(P‐NITROPHENYL)‐2‐(ACETYLAMINO)‐1,3‐PROPANEDIOL AND SODIUM HYPOCHLORITE

Abstract

Bei der Umsetzung des aus (I) erhältlichen Amids (II) mit unterchloriger Säure wird durch Oxi.dation das Phenylketon (III) gebildet.

Crystal structures and other properties of ephedrone (methcathinone) hydrochloride, N-acetylephedrine and N-acetylephedrone

“…Compound 1 was synthesized from ephedrine according to the procedure described in [10] and compared with the materials seized by drug enforcement agencies on the illicit drug market. Compound 2 was obtained according to the procedure reported in [17]. It occurs as a mixture of two rotamers (1.1:1 ratio), as described previously (a 2.8:1 rotamer mixture) [18].…”

“…Physicochemical data pertaining to compounds 1 and 2 were identical with those reported (although compound 2 was obtained in [18] as a colorless liquid). Compound 3 was obtained in [17] as a colorless liquid (no information was given concerning isomer type). We obtained all three compounds as solids, and their structures were corroborated by the crystallographic study.…”

“…The remaining signals are presented in the Supplementary Material. The first 1 H NMR spectra of compound 2 published in [17] and [24] did not show the presence of double signals for particular proton groups; it was suggested that this occurs only in the case of the compound's enantiomer mixture. A subsequent report [25] confirmed the occurrence of rotamers in pure enantiomers of compound 2 and doubling of 1 H NMR spectrum signals.…”