ChemInform Abstract: INTRODUCTION OF A HYDROXYL GROUP INTO A CRESOL MOLECULE

Abstract

Durch eine Rieche‐Formylierung, Baeyer‐Vrlliger‐Oxidation von (II) und Hydrolyse des entstehenden Formiats läßt sich eine Hydroxylgruppe in m‐Stellung zur bereits vorhandenen in (I) einführen.

Synthesis and sensory evaluation of ring-substituted dihydrochalcone sweeteners

“…3-Hydroxy-2',4',6'-tris(benzyloxy)-4-methoxy-6-methylchalcone (5g). Reaction of 3a with 6-methylisovanillin (4g; Kozlova et al, 1981) for 36 h at 40 °C gave, after standard workup, crude product. Impurities were removed by washing with cold diethyl ether/ethyl acetate (10:1) to provide a 66% yield of 5g.…”