The present work is an attempt to compile and analyze the literature pertaining to catalytic vapor phase pyridine synthesis. In the beginning pyridine deriving from coal tar and subsequent years it was developed as catalytic vapor phase synthesis using acetaldehyde, formaldehyde and ammonia provides best prospect for the growing demand. HZSM-5 is the best catalyst present in market to for catalytic pyridine bases; it has unique structural and acidity properties over other catalysts. It is probable that the reactants are adsorbed at catalytic sites, formation of imines precedes cyclisation and desorption from catalytic pores. In this review detail summary of the inventions in chronological order and with their postulates is narrated.