ChemInform Abstract: Melamine and Melamine‐Formaldehyde Polymers as Ligands for Palladium and Application to Suzuki—Miyaura Cross‐Coupling Reactions in Sustainable Solvents.

Abstract

The melamine/PdC(OAc) 2 catalyst is soluble and active in both water and the renewable nontoxic organic solvent ethyl lactate (ELA). Further, it is inexpensive, easy to handle, bench-stable, and effective in catalysis in the presence of a variety of impurities. The reaction of the catalyst with formaldehyde generates an insoluble polymeric catalyst that can be easily recovered and applied in Suzuki-Miyaura cross-coupling [reaction of (XII)]. -(EDWARDS, G. A.; TRAFFORD, M. A.; HAMILTON, A. E.; BUXTON, A. M.; BARDEAUX, M. C.; CHALKER*, J. M.; J. Org. Chem. 79 (2014) 5, 2094-2104, http://dx.