ChemInform Abstract: Microwave Reaction of Diazonium Salts with Nitriles.

Abstract

Microwave chemistry O 0170Microwave Reaction of Diazonium Salts with Nitriles. -Aryldiazonium tetrafluoroborates dissolved in nitriles are converted under microwave irradiation to the corresponding anilides in high to almost quantitative yields. When bromoacetonitrile (IV) is used, quinazoline derivative (V) is formed. The reaction of phenyldiazonium tetrafluoroborate with malononitrile in DMF yields (VIII) as main product and (IX) as by-product. At higher concentrations of phenyldiazonium tetrafluoroborate, (IX) is formed as the main product. -(SAEZ, R.; OTERO, M. D.; BATANERO, B.; BARBA*, F.; J.