ChemInform Abstract: N‐Heterocyclic Carbene Catalyzed Transformations of 3‐Halopropenals to the Equivalents of β‐Acylvinyl Anions.

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

“…Additionally, alkyl-substituted ynals and α-keto esters were not described. Concurrently, Ma and co-workers, building on previous work, reported a highly enantioselective [3 + 2] annulation of β-bromo enals and N- protected isatins to furnish spirooxindole-butenolides, catalyzed by a N- heterocyclic carbene catalyst bearing a hydroxyl moiety ( B 28 ) (Scheme ) …”