ChemInform Abstract: New Octahydropyrido[3,4‐b]acridine Scaffolds for Combinatorial Chemistry.

Abstract

Fused pyridine derivatives R 0450New Octahydropyrido[3,4-b]acridine Scaffolds for Combinatorial Chemistry. -The parent skeleton (III) is prepared by Friedlaender reaction in a completely regioselective manner. Functionalization of the bromine substituents and the secondary amino group allows the preparation of a product library. -(DIEDRICH, C. L.; HAASE, D.;

Total Synthesis of (+)-Shearilicine

“…CataCXium ligand L1 has been utilized extensively for Suzuki, Buchwald–Hartwig, and Sonogashira coupling reactions . We were inspired to test L1 due to successful applications in Heck reactions between allylic alcohols and aryl halides .…”