ChemInform Abstract: One‐Pot Synthesis of Trifluoroacetimidoyl Halides.

Abstract

1993carboxylic acid derivatives carboxylic acid derivatives (acyclic compounds) P 0340 -127One-Pot Synthesis of Trifluoroacetimidoyl Halides. -Trifluoroacetic acid (I) is coupled with aliphatic amines and anilines such as (II) in the presence of carbon tetrachloride or carbon tetrabromide, triphenylphosphine, and triethylamine to produce the trifluoroacetimidoyl halides (III). The reaction failed with carbon tetraiodide and with perfluoropropanoic or perfluorooctanoic acid. The mechanism is discussed.-(TAMURA, K.; MIZUKAMI, H.; MAEDA, K.; WATANABE, H.; UNEYAMA, K.; J. Org. Chem. 58 (1993) 1, 32-35; Dep. Appl. Chem., Fac. Eng., Univ., Okayama 700, Japan; EN)