ChemInform Abstract: One‐Pot Synthesis of Isoxazoles from Enaminones: An Application of Fe(II) as the Catalyst for Ring Expansion of 2H‐Azirine Intermediates.

Abstract

Expansion of 2H-Azirine Intermediates. -A direct one-pot method for the synthesis of isoxazoles from enaminones (I) is described through their PIDA-promoted cyclization to azirines followed by a previously reported FeCl2-catalyzed rearrangement. -(ZHENG, Y.; YANG, C.; ZHANG-NEGRERIE, D.; DU, Y.; ZHAO*, K.; Tetrahedron Lett. 54 (2013) 46, 6157-6160, http://dx.