ChemInform Abstract: Palladium‐Catalyzed Arylation of O,O‐Dialkyl Phosphites under Phase‐Transfer Catalysis Conditions.

Abstract

Palladium-Catalyzed Arylation of O,O-Dialkyl Phosphites underPhase-Transfer Catalysis Conditions.-The palladium-catalyzed arylation of dialkyl phosphites (I), (IV), and (IX) under phase-transfer conditions is studied. The diethyl (I) and diisopropyl phosphites (IX) undergo cross-coupling with aryl halides (II) to give the corresponding arylphosphites (III) and (X), respectively. The iodides prove to be more reactive than the corresponding bromides. The same reaction is observed for dimethyl phosphite (IV), however, the so formed arylphosphites easily undergo acidic hydrolysis to afford the arylphosphonic acids (VI) and (VIII). -(KABACHNIK, M. M.; SOLNTSEVA, M. D.; IZMER, V. V.; NOVIKOVA, Z. S.; BELETSKAYA, I. P.; Zh.